Yes, there are differences between saline and silicone for cosmetic breast augmentation.
Saline and silicone breast implants both have an outer silicone shell. The implants differ in material and consistency, however.
Saline breast implants
Saline implants are filled with sterile salt water. They're inserted empty, and then filled once they're in place.
Saline breast implants are available to women 18 and older for breast augmentation and to women of any age for breast reconstruction.
Silicone breast implants
Silicone implants are pre-filled with silicone gel — a thick, sticky fluid that closely mimics the feel of human fat. Most women feel that silicone breast implants look and feel more like natural breast tissue.
Silicone breast implants are available to women 22 and older for breast augmentation and to women of any age for breast reconstruction.